14-3-3 Protein Antibody

Catalog Number

250447

Unit

0.1 mg

Price

$231.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

The 14-3-3 protein activates tyrosine- and tryptophan hydroxylases in the presence of Ca2+/calmodulin-dependent protein kinase II. This family of proteins mediates transduction by binding to phosphoserine- or phosphothreonine-containing proteins. It is considered to be an adaptor protein being implicated in the regulation of a large number of both general and specialized signaling pathways. Its binding to the partner proteins usually results in the modulation of the activity for the binding partner.

Alternate Names

14-3-3 protein beta/alpha; Protein kinase C inhibitor protein 1; KCIP-1; Protein 1054; YWHAB

Accession No.

P31946

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human 14-3-3 protein.

Application Notes

E: 1:500-1:1,000

WB: 1:200-1:500

IHC: 1:200-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.