14-3-3 Protein Antibody

Catalog Number

253107

Unit

0.1 ml

Price

$330.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA with 50% glycerol. Antibody was purified by immunogen affinity chromatography.

Description

14-3-3 protein beta/alpha (14-3-3) is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. p1433-58 binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. p1433-58 binding generally results in the modulation of the activity of the binding partner. p1433-58 is a negative regulator of osteogenesis. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation.

Alternate Names

14-3-3 protein beta/alpha; Prepronerve growth factor RNH-1; Protein kinase C inhibitor protein 1; KCIP-1;14-3-3 protein beta/alpha, N-terminally processed

Accession No.

P35213

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat 14-3-3 protein.

Application Notes

E: 1:500-1:1,000
WB: 1:1,000

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.