20S Proteasome Antibody

Catalog Number

200179

Unit

0.1 mg

Price

$220.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu and Glu adjacent to the cleavage site at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings resulting in a barrel-shaped structure. The 20S core is part of the clastosomes, cellular bodies that contain ubiquitin conjugates, the proteolytically active 20S core and 19S regulatory complexes, and protein substrates of the proteasome.

Alternate Names

Proteasome subunit alpha 1, 2, 3, 4, 5, 6, 7; Proteasome 20S

Accession No.

P25786

Clonality

ABT-1081

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human 20S Proteasome.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.