ABL2 Antibody

Catalog Number

251598

Unit

0.1 mg

Price

$245.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

Tyrosine-protein kinase ABL2 (ABL2) regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. ABL2 localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. ABL2 phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

Alternate Names

ABL2; Tyrosine-protein kinase ABL2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; Tyrosine-protein kinase ARG; ABLL; ARG

Accession No.

P42684

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ABL2.

Application Notes

E: 1:500-1:1,000
WB: 1:100-1:500
IHC: 1:100-1:500
IP: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.