Alfa-CGRP (A2) Antibody

Catalog Number

250238

Unit

0.2 mg

Price

$690.00

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

Calcitonin gene-related peptide is a 37 amino-acid vasoactive neuropeptide (mw 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects. This antibody binds human alfa-CGRP. Based on inhibition ELISA, this antibody shows full cross-reactivity with rat alfa-CGRP and about about 50% cross-reactivity with human beta-CGRP. Cross-reactivity with coated rat alfa-CGRP is low (8%) and there is no cross-reaction with human amylin.

Product Citations

Recommended Products

250237 Alfa-CGRP (A1) Antibody

Alternate Names

Calcitonin gene-related peptide 1 (Precursor);  CGRP-1;  Alpha-type CGRP

Accession No.

P06881

Clonality

NA

Antigen

Synthetic human adrenomedullin 1-52

Application Notes

Product Cat. No. 250238 binds free alfa-CGRP in solution. Based on inhibition ELISA, the affinity of Product Cat. No. 250238 is at least 24 fold higher than the one of Product Cat. No. 250237. The ELISA dilution guideline applies to human alfa-CGRP coated directly at 1.0  ug/mL. Product Cat. No. 250238 (as capture antibody) forms a sandwich ELISA pair with Product Cat. No. 250237 (as biotinylated detection antibody) for measuring human alfa-CGRP, giving a detection limit of 0.13 nmol/L in an unoptimized buffer assay.

E: 1:2,000

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.