APC Antibody

Rat Monoclonal

Catalog Number

250131

Unit

0.1 mg

Price

$245.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members. This antibody recognizes an epitope in the C-terminal half of the mouse APC in ELISA, Western blot and immunofluorescent staining.



Product Citations

Recommended Products

250130 APC Antibody
200132 APC Antibody

Alternate Names

Adenomatous polyposis coli protein; protein APC; DP2.5; mAPC; Apc

Accession No.

Q61315
NP_031488

Clonality

KT45

Antigen

Recombinant mouse APC[2170-2394] protein

Application Notes

E: 5 μg/ml

WB: 1:2,000

IF: 1:200

 

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

For research use only, not for diagnostic or therapeutic procedures.