ATM Antibody

Rabbit Polyclonal

Catalog Number

200158

Unit

0.1 mg

Price

$220.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

Ataxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma.



Product Citations

Recommended Products


Alternate Names

Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM

Accession No.

Q13315
NP_000042

Clonality

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATM.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

For research use only, not for diagnostic or therapeutic procedures.