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Catalog Number200158 Unit0.1 mg Price$220.00 FormatEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. Data and Images |
DescriptionAtaxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma. Product CitationsRecommended Products Alternate NamesSerine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM Accession No.ClonalityAntigenKLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATM. Application NotesE: 1:500-1:1,000 WB: 1:100-1:500 StorageStore at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
For research use only, not for diagnostic or therapeutic procedures.