Bax Antibody
Mouse Polyclonal Antibody
Cat. No.
250758
Unit
0.1 mg
Price
$307.00
Order
Order directly from
Abbiotec
938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA
Phone: 1 858 586 0500 x100,
1 800 854 7453
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description
Apoptosis regulator BAX (BAX or Bcl-2-like protein 4) accelerates programmed cell death by binding to and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX induces the release of cytochrome c, activation of caspase-3 and apoptosis. BAX forms heterodimers with BCL2, Bcl-X(L), MCL1 and A1 by interacting with BH3 domains in BIK, BID, BAK, and BAD. Defects in BAX are found in some cell lines from hematopoietic malignancies.
