Bmi1 Antibody

Catalog Number

200185

Unit

0.1 mg

Price

$220.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

Polycomb complex protein BMI-1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex that maintains the transcriptionally repressive state of many genes, including Hox genes throughout development. PcG PRC1 complex forms Polycomb bodies that act via chromatin remodeling and histone modification. BMI-1 cooperates with Myc oncogene to produce B-lymphomas.

Alternate Names

Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; PCGF4; RNF51

Accession No.

P35226
NP_005171

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Bmi1.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.