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BMPR1A Antibody

Rabbit Polyclonal Antibody
Cat. No. 
200151
Unit 
0.1 mg
Price $220.00

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Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description 
Upon ligand binding, BMPR1A forms a receptor complex consisting of two type II and two type I transmembrane Ser/Thr kinases. The type I receptors are activated by the type II receptors by using a phosphorylation mechanism, and subsequently bind SMAD transcriptional regulators. Defects in BMPR1A are the cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2, which lead to gastrointestinal, breast, thyroid, endometrial and colon cancers.

Spec Container

For research use only, not for diagnostic or therapeutic procedures.