C3 Complement (2D8) Antibody

Catalog Number

250289

Unit

0.1 mg

Price

$265.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds. This antibody is specific for human C3.

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Alternate Names

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3; C3a anaphylatoxin; Complement C3b alpha chain; Complement C3c alpha chain fragment 1; Complement C3dg fragment; C3d fragment; C3g fragment; C3f fragment; C3c alpha chain fragment 2

Accession No.

P01024

Clonality

2D8

Antigen

C3 isolated from human plasma

Application Notes

Product Cat. No. 250289 reacts strongly with C3. Strong reaction is seen in ELISA with C3 directly coated onto the microtiter well, and also when tested in sandwich ELISA in combination with a polyclonal antibody against C3. In Western blot, Product Cat. No. 250289 reacts with C3 in reduced as well as non-reduced forms.

E: 1:16,000;

WB: 1:1,000

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.