C3 Complement Antibody

Mouse Monoclonal

Catalog Number

250121

Unit

0.1 mg

Price

$245.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Data and Images

Description

The complement component C3 plays a central role in the activation of the complement system. C3 activation by the C3 convertase is the central reaction in both classical and alternative complement pathways. Cleaved C3 produces C3a anaphylatoxin, a mediator of local inflammatory process, and C3b, which binds to cell surface carbohydrates and immune aggregates. Genetic variation in C3 is associated with susceptibility to age-related macular degeneration 9 (ARMD9). This antibody recognizes the human complement C3 in ELISA.



Product Citations

Recommended Products

250123 C4 Complement Antibody
250122 C1 Inhibitor Antibody
250201 C5b-9 Complement Antibody
250137 Anti-mouse IgG Antibody

Alternate Names

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3; C3a anaphylatoxin; Complement C3b alpha chain; Complement C3c alpha chain fragment 1; Complement C3dg fragment; C3d fragment; C3g fragment; C3f fragment; C3c alpha chain fragment 2

Accession No.

P01024
NP_000055

Clonality

KT17

Antigen

Purified human complement C3 protein

Application Notes

E: 5 μg/ml

 

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

For research use only, not for diagnostic or therapeutic procedures.