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CBX4 Antibody

Rabbit Polyclonal Antibody

Cat. No.

251922

Unit

0.1 mg

Price $292.00

Order

Order directly from

Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

E3 SUMO-protein ligase CBX4 (CBX4) is a protein ligase which facilitates SUMO1 conjugation by UBE2I. CBX4 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification of histones; and it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Spec Container

Datasheet

Data Left

Isotype

Rabbit Ig

Applications

IHC

Species Reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Alternate Names

E3 SUMO-protein ligase CBX4; Chromobox protein homolog 4; Polycomb 2 homolog; Pc2; hPc2; CBX4

Data Right

Accession No.

O00257

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CBX4.

Application Notes

E: 1:10,000-1:40,000; WB: 1:200-1:1,000

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Images

The CBX4 Antibody is used in Western blot to detect CBX4 in HEK293 cell lysates.