CD15 (HI98) Antibody

Catalog Number

250948

Unit

0.1 mg

Price

$220.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgM in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by hydroxyapatite chromatography.

Description

The CD15 (HI98) antibody recognizes a 220-kDa carbohydrate antigen–Lacto–N–fucopentaose III, also called Lewis X, X-hapten, and SSEA-I. CD15 antigen is expressed on mature granulocytes (strongly), monocytes (weakly), immature bone marrow cells of myelomonocytic lineage, peripheral blood T lymphocytes (weakly), and some T-cells. CD15 antigen is also expressed on leukemia cells of myelomonocytic origin, Langerhans cells, a variety of carcinoma cells (preferentially adenocarcinomas), and occasionally on lymphocytic leukemia cells. CD15 is absent from B lymphocytes, erythrocytes and platelets. A soluble form of CD15 exists in serum (plasma) besides a membrane form. CD15 antigen plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.

Product Citations

Shen DC. et al. 1989. J. Hematol, 10(7): 350

Guan Q. et al. 1993. Tissue Antigens. 42(4): 365.

Recommended Products

251004 CD15 (HI98) Antibody, FITC
251060 CD15 (HI98) Antibody, PE

Alternate Names

Alpha-(1,3)-fucosyltransferase; Galactoside 3-L-fucosyltransferase; Fucosyltransferase 4; FucT-IV; Fuc-TIV; ELAM-1 ligand fucosyltransferase; CD15; FUT4; ELFT; FCT3A

Accession No.

P22083
NP_002024

Clonality

HI98

Application Notes

Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen and formalin-fixed paraffin sections.

E: 1:500-1:1,000

FACS: 1:200-1:1,000

IHC: 1:200-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.