CD20 (HI47) Antibody

Catalog Number

251064

Unit

2 ml

Price

$275.00

Format

Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

The CD20 (HI47) antibody recognizes a 33-37 kDa type-III non-glycosylated phosphoprotein spanning the cell membrane four times therefore called TM4. CD20 antigen is expressed on pre-B cells, resting/activated B cells and corresponding neoplastic B cells, but is absent from plasma cells. CD20 regulates B lymphocyte activation and proliferation. The antibody also reacts with several dendritic, endothelial, epithelial, activated T cells and macrophages. The antibody stains 8-16% of normal peripheral blood lymphocytes. The CD20 (HI47) Antibody inhibits B lymphocyte activation and proliferation.

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Alternate Names

B-lymphocyte antigen CD20; Membrane-spanning 4-domains subfamily A member 1; B-lymphocyte surface antigen B1; Leu-16; Bp35; MS4A1; CD20

Accession No.

P11836
NP_690605

Clonality

HI47

Antigen

Application Notes

FACS with whole blood: 100 μl blood + 20 μl antibody; FACS with cells: 10E6 cells + 20 μl antibody.

E: 1:500-1:1,000

FACS: 1:200-1:1,000

IHC: 1:200-1:500

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment