CD89 Antibody

Catalog Number

250124

Unit

0.1 mg

Price

$245.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Data and Images

Description

The CD89 antigen (Fc alpha receptor I) binds to the Fc region of immunoglobulins alpha (IgA). CD89 mediates several immune functions including cytokine production. CD89 consists of a membrane-distal Ig-like extracellular domain (EC1), a membrane-proximal Ig-like extracellular domain (EC2), a transmembrane region, and a short cytoplasmic tail. This antibody recognizes the EC1 domain of human CD89 by flow cytometry and also inhibits CD89 functions.

Product Citations

Zhang, W et al. 2000. Clin. Exp. Immunol. 121: 106-111

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250125 CD89 Antibody

Alternate Names

Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89 antigen; FCAR; CD89

Accession No.

P24071
NP_001991

Clonality

MIP7c

Antigen

Soluble human CD89 protein

Application Notes

B: 4 μg/4 x 10⁵ cells

FACS: 1 μg/0.1 ml. This antibody recognizes the EC1 domain of Fc alpha-RI extracellular region.

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.