Delangin-B Antibody

Catalog Number

250132

Unit

0.1 mg

Price

$245.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

Delangin (NPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin complex. Delangin deficiencies are the cause of Cornelia de Lange syndrome type 1 (CDLS1), which is a heterogeneous developmental disorder associated with malformations affecting multiple systems such as member growth, cognitive retardation, cardiac anomalies. This antibody recognizes the isoform B (short form) of human and mouse delangin in Western blot, immunoprecipitation, immunofluorescent staining and immunohistochemistry.

Alternate Names

Nipped-B-like protein; Delangin; SCC2 homolog; NIPBL; IDN3B

Accession No.

Q6KC79
NP_056199

Clonality

KT55

Antigen

Synthetic peptide encompassing a sequence within the C-term region of human delangin protein coupled to BSA.

Application Notes

WB: 1:1,000

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.