Dnmt3b Antibody

Catalog Number

200103

Unit

0.1 mg

Price

$220.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

Dnmt3B is required for genome wide de novo methylation and is essential for development. Defects in Dnmt3B are a cause of immunodeficiency-centromeric instability-facial abnomalies syndrome (ICF), characterized biochemically by hypomethylation of CpG sites in heterochromatin.

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Alternate Names

DNA (cytosine-5)-methyltransferase 3B; Dnmt3b; DNA methyltransferase HsaIIIB; DNA MTase HsaIIIB; M.HsaIIIB

Accession No.

Q9UBC3
NP_008823

Clonality

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Dnmt3b.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.