EB2 Antibody

Rat Monoclonal

Catalog Number

250128

Unit

0.1 mg

Price

$245.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

EB proteins belong to the microtubule plus end tracking family proteins. They interact with cytoplasmic microtubules in interphase cells, with mitotic spindles, and with the adenomatous polyposis coli (APC) tumor suppressor. The end-binding protein 1, 2 and 3 (EB1-3) are involved in microtubule polymerization and stabilization with centrosomes as well as spindle function. The N-terminal domain of EB proteins binds to microtubules whereas the C-terminal domain forms mutually exclusive complexes with APC and DCTN1. This antibody recognizes the human, monkey, mouse and hamster EB2 in ELISA, Western blot, immunoprecipitation and immunofluorescent staining.



Product Citations

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Alternate Names

Microtubule-associated protein RP/EB family member 2; End-binding protein 2; EB2; APC-binding protein EB2; RP1; MAPRE2

Accession No.

Q15555
NP_055083

Clonality

KT52

Antigen

Purified full-length human EB2-GST fusion protein

Application Notes

WB: 1:2,000

IF: 1:200

 

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

For research use only, not for diagnostic or therapeutic procedures.