EB3 Antibody

Catalog Number

250127

Unit

0.1 mg

Price

$245.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

EB proteins belong to the microtubule plus end tracking family proteins. They interact with cytoplasmic microtubules in interphase cells, with mitotic spindles, and with the adenomatous polyposis coli (APC) tumor suppressor. The end-binding protein 1, 2 and 3 (EB1-3) are involved in microtubule polymerization and stabilization with centrosomes as well as spindle function. The N-terminal domain of EB proteins binds to microtubules whereas the C-terminal domain forms mutually exclusive complexes with APC and DCTN1. This antibody recognizes the human EB3 in ELISA, Western blot and immunoprecipitation.

Recommended Products

250126 EB3 Antibody
250128 EB2 Antibody
250129 EB1 Antibody

Alternate Names

Microtubule-associated protein RP/EB family member 3; End-binding protein 3; EB3; EB1 protein family member 3; EBF3; RP3; MAPRE3

Accession No.

Q9UPY8
NP_036458

Clonality

KT53

Antigen

Purified full-length human EB3-GST fusion protein

Application Notes

WB: 1:2,000; This antibody also recognizes an unidentified 28 kDa protein in WB.

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.