Glucosylceramide Synthase Antibody

Rabbit Polyclonal

Catalog Number

250505

Unit

0.1 mg

Price

$265.00

Isotype

Rabbit Ig

Applications

E, WB, IHC

Species reactivity

H, M, R, Other

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Cat. No. 250505: The Glucosylceramide Synthase Antibody is used in Western blot to detect glucosylceramide synthase in mouse brain lysates.Cat. No. 250505: The Glucosylceramide Synthase Antibody is used in Western blot to detect glucosylceramide synthase in mouse brain lysates.
Glucosylceramide Synthase staining in human breast cancer: Paraffin-embedded human breast cancer tissue is stained with Glucosylceramide Synthase Antibody (Cat. No. 250505) used at 1:200 dilution.Glucosylceramide Synthase staining in human breast cancer: Paraffin-embedded human breast cancer tissue is stained with Glucosylceramide Synthase Antibody (Cat. No. 250505) used at 1:200 dilution.

Description

Glucosylceramide synthase (GCS) serves as a flippase and a glucosyltransferase that transfers glucose to ceramide. GCS catalyzes the tranfer of glucose from UDP-glucose to a N-acylsphingosine to form D-glucosyl-N-acylsphingosine.


Alternate Names

Ceramide glucosyltransferase; Glucosylceramide synthase; GCS; UDP-glucose N-acylsphingosine D-glucosyltransferase; UDP-glucose ceramide glucosyltransferase; GLCT-1; UGCG

Accession No.

Q16739

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GCS.

Application Notes

E: 1:500-1:1,000

WB: 1:200-1:500

IHC: 1:200-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Enzymes,  Glycosyltransferases,  Glycan Biosynthesis & Metabolism, Lipid Metabolism

For research use only, not for diagnostic or therapeutic procedures.