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HES-1 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
252142
Unit 
0.1 mg
Price $280.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Transcription factor HES-1 (HES-1) is a transcriptional repressor of genes that require a bHLH protein for their transcription. HES-1 acts as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. HES-1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.