IL-10 Antibody

Rabbit Polyclonal

Catalog Number

250713

Unit

0.1 mg

Price

$231.00

Isotype

Rabbit Ig

Applications

E, WB, IHC

Species reactivity

H, M, R, B, D, P, Rb

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Cat. No. 250713: The IL-10 Antibody is used in Western blot to detect IL-10 in rat pancreas lysates.Cat. No. 250713: The IL-10 Antibody is used in Western blot to detect IL-10 in rat pancreas lysates.IL10 staining in rat colon: Paraffin-embedded rat colon is stained with IL10 Antibody (Cat. No. 250713) used at 1:100 dilution.IL10 staining in rat colon: Paraffin-embedded rat colon is stained with IL10 Antibody (Cat. No. 250713) used at 1:100 dilution.

Description

Interleukin 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. IL-10 has pleiotropic effects in immunoregulation and inflammation such as inhibiting synthesis of IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and helper T-cells. Defects in IL-10 are a cause of susceptibility to Crohn disease, an inflammatory bowel disease.


Product Citations

Agarwal D et al. 2011. Medicine. Basic Research in Cardiology. 106(6): 1069-1085

Tong H et al. 2011. The Anatomical Record. 294(3):445-452

Shi P et al. Hypertension. 2010. 297-303

Alternate Names

Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; IL10

Accession No.

P22301

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-10.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

IHC: 1:200-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Cytokines,  Immune System, Signal Transduction, Signaling Molecules & Interaction

For research use only, not for diagnostic or therapeutic procedures.