L-Ficolin (A1) Antibody

Catalog Number

250217

Unit

0.2 mg

Price

$545.00

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease). This antibody reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3).

Product Citations

Recommended Products

Alternate Names

Ficolin-A; Ficolin-alpha; M-ficolin; Collagen/fibrinogen domain-containing protein 1

Accession No.

O00602

Clonality

NA

Antigen

Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein

Application Notes

Product Cat. No. 250217 is especially well suited as capture antibody in a sandwich ELISA in combination with Product Cat. No. 250218. Furthermore, Product Cat. No. 250217 reacts with recombinant L-Ficolin coated directly into the microtiter well.

E: 1:2,000;

WB: 1:1,000

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.