Ph. 858 586 0500    Toll Free 800 854 7453

NTP Antibody

Rabbit Polyclonal Antibody
Cat. No. 
250794
Unit 
0.1 mg
Price $231.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Neuronal thread protein (NTP) is composed almost entirely of Alu repeat sequences, and the mRNA encoding this protein is expressed in neurons. Overexpression of NTP is associated with neurofibrillary tangles of Alzheimer's disease. Both CSF and urine levels of NTP have been investigated as a biochemical marker of Alzheimer's disease. In vitro studies have also demonstrated that abnormal expression of this protein promotes neuritic sprouting and cell death, which is associated with dementia in Alzheimer's disease.