PAR-2 Antibody

Rabbit Polyclonal

Catalog Number

251547

Unit

0.1 mg

Price

$280.00

Isotype

Rabbit Ig

Applications

E, WB, IHC

Species reactivity

H, M, R

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

PAR-2 staining in human colon cancer: Paraffin-embedded human colon cancer is stained with PAR-2 Antibody (Cat. No. 251547) used at 1:200 dilution.PAR-2 staining in human colon cancer: Paraffin-embedded human colon cancer is stained with PAR-2 Antibody (Cat. No. 251547) used at 1:200 dilution.

Description

Proteinase-activated receptor 2 (PAR-2) is a receptor for trypsin and trypsin-like enzymes coupled to G proteins that stimulate phosphoinositide hydrolysis. PAR-2 plays a role in the regulation of vascular tone, and is widely expressed in tissues with especially high levels in pancreas, liver, kidney, small intestine, and colon.


Alternate Names

PAR-2; Proteinase-activated receptor 2; Thrombin receptor-like 1; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; F2RL1; GPR11; PAR2

Accession No.

P55085

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PAR-2.

Application Notes

E: 1:500-1:1,000
WB: 1:100-1:500
IHC: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

GTP-binding Proteins,  Receptors & Channels,  Signaling Molecules & Interaction

For research use only, not for diagnostic or therapeutic procedures.