PTBP1 Antibody

Catalog Number

200209

Unit

0.1 mg

Price

$220.00

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

Polypyrimidine tract-binding protein 1 (PTBP1) is involved in pre-mRNA splicing by binding to the polypyrimidine tract of introns. PTBP1 promotes the binding of U2 snRNP to pre-mRNA. PTBP1 cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. PTBP1 is a marker of the perinucleolar compartment that caps on surface of nucleolus and contains RNA pol III transcripts and RNA-binding proteins.

Product Citations

Recommended Products

Alternate Names

Polypyrimidine tract-binding protein 1; PTB; Heterogeneous nuclear ribonucleoprotein I; hnRNP I; 57 kDa RNA-binding protein PPTB-1; PTBP1

Accession No.

P26599
NP_114368

Clonality

ABT-1087

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of PTBP1.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.