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RAD17 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
252171
Unit 
0.1 mg
Price $330.00

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Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Cell cycle checkpoint protein RAD17 (RAD17) is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. RAD17 has a weak ATPase activity required for binding to chromatin. RAD17 participates in the recruitment of the RAD1-RAD9-HUS1 complex onto chromatin, and in CHEK1 activation. RAD17 is a sensor of DNA replication progression, and is involved in homologous recombination.