RAD17 Antibody
Rabbit Polyclonal Antibody
Cat. No.
252171
Unit
0.1 mg
Price
$330.00
Order
Order directly from
Abbiotec
938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA
Phone: 1 858 586 0500 x100,
1 800 854 7453
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description
Cell cycle checkpoint protein RAD17 (RAD17) is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. RAD17 has a weak ATPase activity required for binding to chromatin. RAD17 participates in the recruitment of the RAD1-RAD9-HUS1 complex onto chromatin, and in CHEK1 activation. RAD17 is a sensor of DNA replication progression, and is involved in homologous recombination.
