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Synaptojanin 1 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
253221
Unit 
0.1 ml
Price $330.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Synaptojanin is a phosphatidylinositol phosphatase involved in clathrin-mediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms; one that is ~ 145 kDA and is exclusively expressed in neurons, and a 70 kDa isoform which is expressed in non neuronal, peripheral tissues. Defects in synaptojanin have been linked to Donwn’s syndrome.