Amylin Peptide

Catalog Number

350015

Unit

1 mg

Price

$325.00

Description

Amylin, also called Islet or insulinoma amyloid polypeptide (IAPP), is a 37-amino acid monomeric polypeptide isolated from pancreatic amyloid, which is commonly found in the islet of patients with diabetes mellitus type II and in insulinomas. Amylin is derived from a larger propeptide precursor of 89 amino acids in humans. Immunostaining of amylin is found in islet amyloid and in cells of the islets of Langherans, where it colocolizes with insulin in islet B cells. This peptide corresponds to full-length amylin (residues 34-70 of human amylin precursor) with a Cys2-Cys7 disulfide bridge and an amidated C-terminus end.

Format

Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

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Alternate Names

Islet amyloid polypeptide; Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide; IAPP

Accession No.

P10997
NP_000406

MW

3906.3 g/mol

Sequence

Human: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 or KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2 (Cys2-Cys7)

Composition

C165H262O50N56S2

Purity

Purity > 95% by HPLC

Solubility

We recommend using 100% dimethyl sulfoxide (DMSO).

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.

For research use only, not for diagnostic or therapeutic procedures.