Abbiotec, LLC
7955 Dunbrook Road, Suite B
San Diego, CA 92126
Phone: 1 858 586 0500
Toll Free: 1 800 854 7453
Fax: 1 858 586 6252
Email Us
APC Peptide
Catalog Number350494 Unit0.1 mg Price$50.00 |
Description
The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members.
FormatEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. Data and Images |
Product CitationsRecommended ProductsAlternate NamesAdenomatous polyposis coli protein; protein APC; DP2.5 Accession No.MW1990.2 g/mol SequenceThe synthetic peptide used to raise the antibody Cat. No. 200132 is selected from a sequence within the N-term region of human APC. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. CompositionC101H148N22O31S1 PurityPurity > 80% by HPLC SolubilityDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. StorageStore at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
For research use only, not for diagnostic or therapeutic procedures.