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Asp371 Tyrosinase [369-377] Peptide
Catalog Number350002 Unit1 mg Price$89.00 |
Description
The peptide is a tumor antigenic peptide that activates antigen-presenting cells (APC) and is displayed on melanoma tumor cells. The sequence corresponds to the mutated N371D glycosylation site analog within residues 369-377 of human tyrosinase (TYR). The TYR enzyme is an oxidase that is involved in the formation of pigments such as melanins and other polyphenolic compounds by tyrosine conversion. TYR defects are the cause of oculocutaneous albinism, characterized by the absence of pigment in hair, skin and eyes.
FormatEach vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. Data and Images |
Product CitationsRecommended Products Alternate NamesTyrosinase; Monophenol monooxygenase; Tumor rejection antigen AB; SK29-AB; LB24-AB; TYR Accession No.MW1031.2 g/mol SequenceTyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val or YMDGTMSQV CompositionC42H66N10O16S2 PurityPurity > 95% by HPLC SolubilityDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. StorageStore at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
For research use only, not for diagnostic or therapeutic procedures.