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Beta Amyloid [1-40] Peptide
Catalog Number350016 Unit1 mg Price$245.00 |
Description
Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This peptide corresponds to the human beta-amyloid 1-40 peptide.
FormatEach vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. Data and Images |
Product CitationsRecommended Products Alternate NamesBeta-amyloid protein 40; Beta-APP40; P3(40); Amyloid beta A4 protein; APP; ABPP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; Protease nexin-II; PN-II; APPI; PreA4 Accession No.MW4329.9 g/mol SequenceHuman: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val CompositionC194H295N53O58S1 PurityPurity > 95% by HPLC SolubilityWe recommend using 100% dimethyl sulfoxide (DMSO). StorageStore at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
For research use only, not for diagnostic or therapeutic procedures.