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CYLD Peptide
Catalog Number350498 Unit0.1 mg Price$50.00 |
Description
CYLD is a negative regulator of TRAF2 and NF-kappa B signaling pathway. CYLD has a deubiquitinating activity that is directed towards non-Lys48-linked polyubiquitin chains. Defects in CYLD are the cause of familial cylindromatosis, a highly tumor type-specific disorder.
FormatEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. Data and Images |
Product CitationsRecommended ProductsAlternate NamesProbable ubiquitin carboxyl-terminal hydrolase CYLD; Ubiquitin thioesterase CYLD; Ubiquitin-specific-processing protease CYLD; Deubiquitinating enzyme CYLD; CYLD1 Accession No.MW2185.4 g/mol SequenceThe synthetic peptide used to raise the antibody Cat. No. 200136 is selected from a sequence within the N-term region of human CYLD. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. CompositionC97H141N25O31S1 PurityPurity > 80% by HPLC SolubilityDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. StorageStore at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
For research use only, not for diagnostic or therapeutic procedures.