Download DatasheetFANCL Peptide
Synthetic Peptide
Blocking Peptide
Cat. No.
350524
Unit
0.1 mg
Price
$50.00
Order
Order directly from
Abbiotec
7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA
Phone: 1 858 586 0500,
1 800 854 7453
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description
Fanconi anemia group L protein (FANCL) is an ubiquitin ligase that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway. FANCL is required for proper primordial germ cell proliferation in the embryonic stage. Defects in FANCA are the cause of Fanconi anemia, a syndrome characterized by pancytopenia, congenital malformations and predisposition to cancers caused by a hypersensitivity to DNA-damaging agents, chromosomal instability and defective DNA repair.