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SMAD4 Peptide
Blocking
Catalog Number350515 Unit0.1 mg Price$50.00 FormatEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
Description***DISCONTINUED PRODUCT*** SMAD4 is a common mediator of signal transduction by TGF-beta superfamily and acts as a tumor suppressor. SMAD4 promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA. Defects in SMAD4 are the cause of pancreatic carcinoma, juvenile polyposis syndrome and telangiectasia. Recommended ProductsAccession No.MW1962.2 g/mol SequenceThe synthetic peptide used to raise the antibody Cat. No. 200153 is selected from a sequence within the C-term region of human SMAD4. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. CompositionC87H132N24O26S1 PurityPurity > 80% by HPLC SolubilityDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. StorageStore at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
| Transcription Factors, Cancers, Cell Communication, Cell Growth & Death, Signal Transduction | |
For research use only, not for diagnostic or therapeutic procedures.