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Antibodies for human complement components: C1 inhibitor, C3, C4, C5b-9, Factor B, Factor I, Properdin.

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ABBIOTEC
7985 Dunbrook Road, Suite A
San Diego, CA 92126

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TIMP-3 Peptide

Synthetic Peptide

Blocking Peptide

Cat. No.

350574

Unit

0.1 mg

Price $80.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

Tissue inhibitor of metalloproteinases 3 (TIMP-3) binds to metalloproteinases such as collagenases and irreversibly inactivates the proteases. TIMP-2 is involved in the extracellular matrix remodeling by binding to MMP-1, -2, -3, -7, -9, -13, -14 and -15. Defects in TIMP-3 are the cause of Sorsby fundus dystrophy (SFD), a macular disorder leading to vision loss.

Spec Container

Datasheet

Format

Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Metalloproteinase inhibitor 3; Tissue inhibitor of metalloproteinases 3; TIMP-3; Protein MIG-5; TIMP3

Accession No.

P35625

1373.5 g/mol

Sequence

The synthetic peptide used to raise the antibody Cat. No. 250885 is selected from a sequence within the C-term region of human TIMP-3. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Composition

C62H84N16O18S1

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

For research use only, not for diagnostic or therapeutic procedures.

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TIMP-3 Peptide

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