Published on Abbiotec™ (http://www.abbiotec.com)
Actin Antibody

Catalog Number

251707

Unit

0.1 mg

Price

$245.00

Isotype

Mouse IgG2a

Applications

E, WB, IHC

Species reactivity

H, M, R, Ck

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Defetcs in beta-actin are a cause of dystonia juvenile-onset (DYTJ). DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures.


Alternate Names

Actin, cytoplasmic 1; Beta-actin; ACTB

Accession No.

P60709 [1]

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human beta-actin.

Application Notes

E: 1:500-1:1,000
WB: 1:100-1:500
IHC: 1:100-1:500
ICC: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Cytoskeleton Proteins [2],  Cell Communication [3], Cell Motility [4], Immune System [5], Infectious Diseases [6]

Source URL: http://www.abbiotec.com/antibodies/actin-antibody

Links:
[1] http://www.uniprot.org/uniprot/P60709
[2] http://www.abbiotec.com/protein-family/cytoskeleton-proteins
[3] http://www.abbiotec.com/pathways/gtpase
[4] http://www.abbiotec.com/pathways/stem-cell-markers
[5] http://www.abbiotec.com/pathways/immune-system
[6] http://www.abbiotec.com/pathways/infectious-diseases