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CAM Ligands

MMP-2 Antibody

$231.00
SKU: 250752

Matrix metalloproteinase protein family (MMP) is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in diseases such as arthritis and metastasis. Most MMPs are secreted as inactive precursors which are activated upon cleavage by extracellular proteinases. MMP-2 is an enzyme that degrades gelatin type I and collagen types IV, V, VII and X, and KiSS1. MMP-2 is also a ligand for the integrin alpha-V/beta-3.

MMP-2 staining in human stomach cancer. Paraffin-embedded human stomach cancer is stained with MMP-2 Antibody (Cat. No. 250752) used at 1:200 dilution.
List price: $0.00
Price: $231.00

MMP-1 (mouse) Antibody

$231.00
SKU: 250750

Matrix metalloproteinase family members are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Matrix metalloproteinase-1 (Interstitial collagenase A/B or MMP-1) cleaves collagens of types I, II and III. This antibody is specific for mouse MMP-1.

MMP-1 staining in mouse lung. Paraffin-embedded mouse lung is stained with MMP-1 Antibody (Cat. No. 250750).
The MMP-1 (mouse) Antibody is used in Western blot to detect MMP-1 in mouse liver lysates.
List price: $0.00
Price: $231.00

CD61 Antibody

$231.00
SKU: 250732
CD61, also called integrin beta-3, belongs to the integrin protein family that participates in cell adhesion and cell-surface mediated signalling by forming heterodimers of alpha and beta integrin chains. Integrin alpha-V/beta-3 is a receptor for cytoactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin.
CD61 staining in human liver cancer. Paraffin-embedded human liver cancer is stained with CD61 antibody (Cat. No. 250732) used at 1:200 dilution.
List price: $0.00
Price: $231.00

CD34 Antibody

$231.00
SKU: 250591

Hematopoietic progenitor cell antigen CD34 is a leukocyte antigen expressed in various cell types including hematopoietic cells. Antibodies against CD34 are used to identify lymphohematopoietic stem/progenitor cells. CD34 is likely an adhesion molecule with a role in early hematopoiesis by mediating attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells.

Paraffin-embedded mouse brain is stained with CD34 Antibody (Cat. No. 250591) used at 1:100 dilution.
List price: $0.00
Price: $231.00

CD31 Antibody

$231.00
SKU: 250590

CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular expression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g.

CD31 staining in mouse melanoma. Paraffin-embedded mouse melanoma cells are stained with CD31 Antibody (Cat. No. 250590) used at 1:200 dilution.
List price: $0.00
Price: $231.00

CD31 (N-term) Antibody

$231.00
SKU: 250589
CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular expression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g.
CD31 staining in rat fat tissue. Paraffin-embedded rat fat tissue is stained with CD31 (N-term) Antibody (Cat. No. 250589) used at a 1:200 dilution.
List price: $0.00
Price: $231.00

C5a Complement Antibody

$231.00
SKU: 250565
C5 is part of the membrane attack complex (MAC) of the complement system. C5 is split into C5a and C5b by the C5 convertases from the classical and the alternative complement pathway and the C5b fragment initiates the assembly of the terminal MAC (C5b-C9). The molecular mass of C5 is 190 kDa. C5a is later cleaved into C5 anaphylatoxin, a mediator of local inflammation, and C5a'.
C5a staining in rat brain. Paraffin-embedded rat brain is stained with C5a antibody (Cat. No. 250565) used at 1:200 dilution.
250565: The C5a Antibody is used in Western blot to detect C5a in rat pancreas lysate.
List price: $0.00
Price: $231.00

MAG (C-term) Antibody

$231.00
SKU: 250518
Myelin-associated glycoprotein (MAG) is an adhesion molecule in postnatal neural development that mediates sialic acid dependent cell-cell interactions between neuronal and myelinating cells. MAG preferentially binds to alpha-2,3-linked sialic acid. Isoform L-MAG is critical for the formation of myelin in the CNS, whereas isoform S-MAG is sufficient to maintain the integrity of myelin in PNS. MAG belongs to the immunoglobulin superfamily SIGLEC, sialic acid binding lg-like lectin.
Paraffin-embedded mouse brain is stained with MAG Antibody (Cat. No. 250518) used at 1:400 dilution.
List price: $0.00
Price: $231.00

Fibronectin Antibody

$231.00
SKU: 250500
Fibronectin is an adhesive glycoprotein with a molecular mass of 440 kDa. It is believed to be important for the formation of a provisional matrix that promotes cell adhesion and migration during wound healing. Its age-dependent increase in plasma and tissues may be accompanied in pathological states, especially in tumor growth, by its proteolytic breakdown by a number of neutral proteases. It has also shown that several of its proteolytic breakdown products exhibit unexpected and mostly harmful biological activities.
Fibronectin staining of rat kidney. Paraffin-embedded rat kidney tissue is stained with Fibronectin Antibody (Cat. No. 250500) used at 1:200 dilution.
List price: $0.00
Price: $231.00

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