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CAM Ligands

Human PDGF-AA

$235.00
SKU: 600163
PDGF (Platelet-derived growth factor) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by Interleukin-1, Interleukin-6, TNF-alpha, TGF-beta and EGF. Recombinant Human Platelet Derived Growth Factor-AA is a homodimeric non-glycosylated polypeptide chain containing 2 x 125 amino acids with a total MW of 28,511 Da.
List price: $0.00
Price: $235.00

Human Galectin-1

$235.00
SKU: 600116
Human Galectin-1 belongs to a large family of carbohydrate-binding proteins that contain structural similarities in their carbohydrate recognition domains. Galectin-1, also known as L-14, BHL or galaptin, is a monomer or a homodimer found in a wide varity of cells and tissue types. Galectin-1 controls cell growth and proliferation and induces apoptosis of activated T cells. It can also modulate cytokine secretion or inhibit pro-inflammatory cytokine production. Galectin-1 plays an important role in acute and chronic inflammation.
List price: $0.00
Price: $235.00

CD34 Antibody

$315.00
SKU: 254507
Hematopoietic progenitor cell antigen CD34 is a leukocyte antigen expressed in various cell types including hematopoietic cells. Antibodies against CD34 are used to identify lymphohematopoietic stem/progenitor cells. CD34 is likely an adhesion molecule with a role in early hematopoiesis by mediating attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells.
List price: $0.00
Price: $315.00

COL1A1 Telopeptide Antibody

$330.00
SKU: 253123
Collagen 1, alpha 1 propeptide (COL1A1) is a member of group I collagen (fibrillar forming collagen). Defects in COL1A1 are the cause of Caffey disease (CAFFD), also known as infantile cortical hyperostosis. Caffey disease is characterized by an infantile episode of massive subperiosteal new bone formation that typically involves the diaphyses of the long bones, mandible and clavicles.
List price: $0.00
Price: $330.00

COL1A1 Propeptide Antibody

$330.00
SKU: 253122
Collagen 1, alpha 1 propeptide (COL1A1) is a member of group I collagen (fibrillar forming collagen). Defects in COL1A1 are the cause of Caffey disease (CAFFD), also known as infantile cortical hyperostosis. Caffey disease is characterized by an infantile episode of massive subperiosteal new bone formation that typically involves the diaphyses of the long bones, mandible and clavicles.
List price: $0.00
Price: $330.00

CD86 (1B3) Antibody

$308.00
SKU: 253066

CD86 (T-lymphocyte activation antigen CD86) is a receptor for CD28 or CTLA-4. It is involved in the co-stimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production. CD86 plays a critical role in the early events of T-cell activation and costimulation of naive T-cells.

The CD86 (1B3) Antibody (Cat. No. 253066) is used in Western blot to detect CD86 in mouse lymphocytic leukemia L1210 (1) and human T-lymphoblast MOLT-4 (2) cell lysates.
List price: $0.00
Price: $308.00

CDH1 (7A2) Antibody

$308.00
SKU: 253086
CDH1 (Cadherin-1) is a cell adhesion protein, member of the cadherin family. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers.
List price: $0.00
Price: $308.00

CDH1 (7H12) Antibody

$308.00
SKU: 253080
CDH1 (Cadherin-1) is a cell adhesion protein, member of the cadherin family. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers.
List price: $0.00
Price: $308.00

VCAM1 (6G9) Antibody

$308.00
SKU: 253005
VCAM-1 (Vascular cell adhesion molecule 1) is a member of the Ig superfamily that plays an important role in cell-cell recognition. VCAM-1 interacts with beta-1 integrin (VLA4) on leukocytes to mediate adhesion and signal transduction during leukocyte-endothelial cell adhesion. VCAM-1 is likely involved in atherosclerosis and rheumatoid arthritis.
List price: $0.00
Price: $308.00

CDH2 (5D5) Antibody

$308.00
SKU: 253002
N-cadherin (CD325) is a calcium dependent cell adhesion protein. CD325 preferentially interacts with itself in a homophilic manner and contributes to the sorting of heterogeneous cell types. CD325 may be involved in neuronal recognition mechanism. In hippocampal neurons CD325 regulates dendritic spine density.
List price: $0.00
Price: $308.00

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