Cellular Antigens

Pathway and Disease

Signaling Molecules and Interaction

Format

Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

Alternate Names

NONE

Composition

C30H50N8O7

Sequence

H-Ser-Phe-Leu-Leu-Arg-OH or H-SFLLR-OH

Purity

Purity > 95% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

634.78 g/mol

Unit

1 mg

Accession No.

BMPR1A Peptide

$50.00

SKU: 350513

Upon ligand binding, BMPR1A forms a receptor complex consisting of two type II and two type I transmembrane Ser/Thr kinases. The type I receptors are activated by the type II receptors by using a phosphorylation mechanism, and subsequently bind SMAD transcriptional regulators. Defects in BMPR1A are the cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2, which lead to gastrointestinal, breast, thyroid, endometrial and colon cancers.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Signal Transduction

Signaling Molecules and Interaction

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Bone morphogenetic protein receptor type IA; Serine/threonine-protein kinase receptor R5; SKR5; Activin receptor-like kinase 3; ALK-3; CD292 antigen; BMPR1A; ACVRLK3

Composition

C77H126N22O34S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200151 is selected from a sequence within the N-term region of human BMPR1A. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1936 g/mol

Unit

0.1 mg

Accession No.

P36894

E-cadherin Peptide

$50.00

SKU: 350496

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers. This antibody may cross-react with cadherin-2, 3 and 4.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

CAM Ligands

Cell Adhesion Molecules

Pathway and Disease

Cancers

Cell Communication

Signaling Molecules and Interaction

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Epithelial cadherin; Uvomorulin; Cadherin-1; CAM 120/80; CD324 antigen; CDH1; CDHE; UVO

Composition

C89H125N25O34S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200134 is selected from a sequence within the C-term region of human E-cadherin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

2121.1 g/mol

Unit

0.1 mg

Accession No.

P12830

KIT Peptide

$50.00

SKU: 350473

KIT is the receptor for stem cell factor (mast cell growth factor). KIT has a tyrosine protein kinase activity. Defects in KIT are a cause of piebaldism (lack of melanocytes), gastrointestinal stromal tumors and testicular tumors.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Endocrine System

Immune System

Signaling Molecules and Interaction

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Mast/stem cell growth factor receptor; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen; KIT

Composition

C80H128N24O29S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200111 is selected from a sequence within the C-term region of human KIT. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1922.1 g/mol

Unit

0.1 mg

Accession No.

P10721

INSR Peptide

$50.00

SKU: 350472

INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cell Communication

Endocrine System

Metabolic Disorders

Neurodegenerative Disorders

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Insulin receptor; CD220 antigen; IR; INSR

Composition

C87H138N24O25S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200110 is selected from a sequence within the N-term region of human INSR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1952.2 g/mol

Unit

0.1 mg

Accession No.

P06213

IGF1R Peptide

$50.00

SKU: 350471

IGF1R binds insulin-like growth factor 1 (IGF1) with high affinity and IGF2 with low affinity. The receptor has a tyrosine protein kinase activity necessary for the activation of the IGF1-stimulated downstream signaling cascade.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Cell Communication

Nervous and Sensory Systems

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Insulin-like growth factor I receptor; CD221 antigen; IGF-I receptor; IGF1R

Composition

C72H125N25O24S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200109 is selected from a sequence within the C-term region of human IGF1R. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1757 g/mol

Unit

0.1 mg

Accession No.

P08069

FGFR4 Peptide

$50.00

SKU: 350469

FGFR4 is a receptor for acidic fibroblast growth factor but does not bind to basic fibroblast growth factor.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

CAM Ligands

Cell Adhesion Molecules

Pathway and Disease

Cell Motility

Signal Transduction

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Fibroblast growth factor receptor 4; FGFR-4; CD334 antigen; FGFR4; JTK2; TKF

Composition

C77H117N29O23S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200107 is selected from a sequence within the N-term region of human FGFR4. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory