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Cytokines

IGF1 Antibody

$231.00
SKU: 250710
Insulin-like Growth Factors IGF1 and IGF2 share 76% sequence identity and are 50% related to pro-insulin. They are non-glycosylated, single-chain proteins of 70 and 76 amino acids in length respectively. IGF1 functions as an autocrine regulator of growth in various tissues, whereas IGF2 is found in placenta. Defects in IGF1 are the cause of insulin-like growth factor I deficiency defined by growth retardation, sensorineural deafness and mental retardation.
List price: $0.00
Price: $231.00

KL-1 Peptide

$60.00
SKU: 350236
KL-1 Peptide stimulates proliferation of Mast cells. It also mediates cell-cell adhesion.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $60.00
Protein Family 
CAM Ligands
Cytokines
Pathway and Disease 
Endocrine System
Immune System
Signaling Molecules and Interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Kit ligand; C-kit ligand; Stem cell factor; SCF; Mast cell growth factor; MGF; KITLG; MGF; SCF
Composition 
C53H90N16O18
Sequence 
Human: H-Leu-Pro-Pro-Val-Ala-Ala-Ser-Ser-Leu-Arg-Asn-Asp-OH or H-LPPVAASSLRND-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
1239.4 g/mol
Unit 
1 mg
Accession No.  
P21583

bFGF Peptide

$80.00
SKU: 300100
Basic fibroblast growth factor (bFGF or FGF2), also called heparin-binding growth factor 2 is an angiogenic agent in vivo and potent mitogen for a variety of cell types in vitro. bFGF activates the MAP kinase signaling pathway and plays a role in synaptic transmission. In additon bFGF induces cell proliferation and binds heparin more strongly than aFGF.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Protein Family 
Cytokines
CAM Ligands
Pathway and Disease 
Signal Transduction
Cancers
Cell Motility
Cell Growth and Death
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Heparin-binding growth factor 2; HBGF-2; Basic fibroblast growth factor; BFGF; Prostatropin; FGF2; FGFB
Composition 
C53H83N17O19
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 250559 is selected from a sequence within the center region of human bFGF. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1424.7 g/mol
Unit 
0.1 mg
Accession No.  
P09038

RC-160 Peptide

$150.00
SKU: 350357
RC-160 is the receptor for TNFSF8/CD30L. It may play a role in the refulation of cellular growth and transformation of activeated lymphoblasts.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $150.00
Protein Family 
Cellular Antigens
Receptors and Channels
Cytokines
Pathway and Disease 
Signaling Molecules and Interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Tumor necrosis factor receptor superfamilyn member 8; CD30L receptor; Lymphocyte activation antigen CD30; Tnfrsf8; Cd30
Composition 
C57H68N12O9S2
Sequence 
Rat: H-D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 (Cys2-Cys7) or H-fCYwKVCW- NH2 (Cys2-Cys7)
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
1129.4 g/mol
Unit 
1 mg
Accession No.  
P97525

Leptin [116-130] Peptide (Mouse)

$190.00
SKU: 350239
Leptin [116-130] Peptide (Mouse) may act as part of signaling pathway that regulates the size of the adipose depot in mice.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $190.00
Protein Family 
Cytokines
Pathway and Disease 
Signal Transduction
Signaling molecules and interaction
Endocrine Systym
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Leptin; Obesity factor; Lep; Ob
Composition 
C64H107N18O25S1
Sequence 
Mouse: H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-OH or H-SCSLPQTSGLQKPES-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
1560.74 g/mol
Unit 
1 mg
Accession No.  
P41160

Leptin [22-56] Peptide

$335.00
SKU: 350240
Leptin [22-56] Peptide may act as part of signaling pathway that regulates the size of the adipose depot.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $335.00
Protein Family 
Cytokines
Pathway and Disease 
Signal Transduction
Signaling molecules and interaction
Endocrine Systym
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Leptin; Obesity factor; Obese protein; LEP; OB; OBS
Composition 
C171H298N50O56
Sequence 
Human: H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH or H-VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQK-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
3950.6 g/mol
Unit 
1 mg
Accession No.  
P41159

ACVR2B 293 Cell Lysate

$672.00
SKU: 400459
Antigen standard for activin A receptor, type IIB (ACVR2B) is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid (True ORF cDNA clone RC212816, OriGene Technologies, Inc.) and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
List price: $0.00
Image 
ACVR2B lysate validation: The ACVR2B 293 Cell Lysate (lane B) and Control Vector Cell Lysate (lane A) are used in Western blot to detect tagged-ACVR2B with a DDK Antibody.
Subcategory 
Cell Lysate
Price: $672.00
Protein Family 
Enzymes
Cytokines
Receptors and Channels
Protein Kinases
Pathway and Disease 
Signaling Molecules and Interaction
Signal Transduction
ORF Clone URL 
http://www.origene.com/orf_clone/trueclone/accession/NM_001106/RC212816.aspx
Format 
This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Applications 
ELISA
WB
IP
Alternate Names 
activin receptor type-2B; ACVR2B; ActR-IIB; ACTRIIB; MGC116908
Application Notes 
WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Storage 
Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Release Date 
Thursday, December 13, 2012
Unit 
0.1 mg
Accession No.  
NP_001097

Human CD40L

$235.00
SKU: 600103

CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2. Recombinant Human CD40L produced in E.

List price: $0.00
Price: $235.00

Human LDL-PLA2

$235.00
SKU: 600272

LP-PLA2 is an enzyme produced by inflammatory cells and hydrolyzes oxidised phospholipids in low-density lipoprotein (LDL). LP-PLA2 travels in the blood mainly with LDL and less than 20% is associated with high-density lipoprotein. LP-PLA2 is involved in the development of atherosclerosis and is a marker for cardiac disease. Recombinant LP-PLA2 comprises a 420 amino acid fragment (22-441) corresponding to the mature LP-PLA2 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.

List price: $0.00
Price: $235.00

Human PDGF-AB

$235.00
SKU: 600164

PDGF (Platelet-derived growth factor) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by Interleukin-1, Interleukin-6, TNF-alpha, TGF-beta and EGF. Recombinant Human PDGF-AB is a heterodimeric non-glycosylated polypeptide chain containing 234 amino acids consisting of 13.3kDa alpha-chain and 12.2 beta-chain with a total MW of 25.5 kDa.

List price: $0.00
Price: $235.00

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