Enzymes

Pathway and Disease

Cancers

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

DNA-repair protein complementing XP-C cells; Xeroderma pigmentosum group C-complementing protein; p125; XPC; XPCC

Composition

C65H105N21O34S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200169 is selected from a sequence within the C-term region of human XPC. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1756.7 g/mol

Unit

0.1 mg

Accession No.

Q01831

XPA Peptide

$50.00

SKU: 350530

Xeroderma pigmentosum group A-complementing protein (XPA) is involved in DNA excision repair by binding to damaged sites with various affinities depending on photoadduct and transcriptional state. Defects in XPA are a cause of xeroderma pigmentosum complementation group A characterized by solar sensitivity and skin cancer predisposition.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

DNA-repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein; XPA; XPAC

Composition

C93H137N25O35S2

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200168 is selected from a sequence within the C-term region of human XPA. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

2229.3 g/mol

Unit

0.1 mg

Accession No.

P23025

MLH1 Peptide

$50.00

SKU: 350529

DNA mismatch repair protein Mlh1 (MLH1) is involved in the repair of DNA mismatches. MLH1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2, Turcot syndrome, Muir-Torre syndrome, including brain, colorectal, breast and endometrial tumors.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

DNA mismatch repair protein Mlh1; MutL protein homolog 1; MLH1; COCA2

Composition

C80H123N25O24S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200167 is selected from a sequence within the C-term region of human MLH1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1851 g/mol

Unit

0.1 mg

Accession No.

P40692

MSH2 Peptide

$50.00

SKU: 350528

DNA mismatch repair protein Msh2 (MSH2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary non-polyposis colorectal cancer type 1 and endometrial cancers.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

DNA mismatch repair protein Msh2; MutS protein homolog 2; MSH2

Composition

C87H157N25O26S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200166 is selected from a sequence within the C-term region of human MSH2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

2001.4 g/mol

Unit

0.1 mg

Accession No.

P43246

WRN Peptide

$50.00

SKU: 350527

Werner syndrome ATP-dependent helicase (WRN) is essential for the formation of DNA replication focal centers and associates with foci elements generating binding sites for RPA. Defects in WRN are a cause of Werner syndrome, a multiple age-related disorders, including atherosclerosis, cancer, diabetes and osteoporosis.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Metabolic Disorders

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Werner syndrome ATP-dependent helicase; WRN; RECQ3; RECQL2

Composition

C94H141N21O28S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200165 is selected from a sequence within the N-term region of human WRN. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

2045.3 g/mol

Unit

0.1 mg

Accession No.

Q14191

RecQL4 Peptide

$50.00

SKU: 350526

RecQ protein-like 4 (RecQ4) is a DNA-dependent ATPase that modulates chromosome segregation. Defects in RecQ4 are the cause of Rothmund-Thomson, Rapadilino, and Baller-Gerold syndromes, dermatological, aplasia and cranial disorders respectively.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

ATP-dependent DNA helicase Q4; RecQ protein-like 4; RecQ4; RTS; RECQL4; RECQ4

Composition

C74H120N24O31S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200164 is selected from a sequence within the N-term region of human RecQL4. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1873.9 g/mol

Unit

0.1 mg

Accession No.

O94761

NBS1 Peptide

$50.00

SKU: 350525

Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11/RAD50/NBN (MRN) complex, which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. NBS1 modulates the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. Defects in NBS1 are the cause of Nijmegen breakage syndrome, cancer predisposition, and anemia.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Replication and Repair

Signaling Molecules and Interaction

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Nibrin; Nijmegen breakage syndrome protein 1; Cell cycle regulatory protein p95; NBN; NBS; NBS1; P95

Composition

C99H150N26O31S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200163 is selected from a sequence within the C-term region of human NBS1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

2232.5 g/mol

Unit

0.1 mg

Accession No.

O60934

FANCL Peptide

$50.00

SKU: 350524

Fanconi anemia group L protein (FANCL) is an ubiquitin ligase that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway. FANCL is required for proper primordial germ cell proliferation in the embryonic stage. Defects in FANCA are the cause of Fanconi anemia, a syndrome characterized by pancytopenia, congenital malformations and predisposition to cancers caused by a hypersensitivity to DNA-damaging agents, chromosomal instability and defective DNA repair.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Ubiquitins

Pathway and Disease

Cancers

Folding

Sorting and Degradation

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

E3 ubiquitin-protein ligase FANCL; Fanconi anemia group L protein; Fanconi anemia-associated polypeptide of 43 kDa; FAAP43; FANCL; PHF9

Composition

C85H135N27O29S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200162 is selected from a sequence within the N-term region of human FANCL. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

2031.2 g/mol

Unit

0.1 mg

Accession No.

Q9NW38

FANCA Peptide

$50.00

SKU: 350523

Fanconi anemia group A protein (FANCA) is a DNA repair protein that operates in a postreplication repair or a cell cycle checkpoint function. FANCA is involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are the cause of Fanconi anemia, a syndrome characterized by pancytopenia, congenital malformations and predisposition to cancers caused by a hypersensitivity to DNA-damaging agents, chromosomal instability and defective DNA repair.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Fanconi anemia group A protein; Protein FACA; FANCA; FAA; FACA; FANCH

Composition

C76H124N24O30S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200161 is selected from a sequence within the C-term region of human FANCA. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory

MW

1886 g/mol

Unit

0.1 mg

Accession No.

O15360

BLM Peptide

$50.00

SKU: 350521

BLM, a helicase protein from the RecQ subfamily, participates in DNA replication and repair with a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. BLM is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in BLM are the cause of bloom syndrome, characterized by growth deficiency, skin pigmentation disorders, predisposition to malignancy and chromosomal instability.

List price: $0.00

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Price: $50.00

Protein Family

Pathway and Disease

Cancers

Replication and Repair

Format

Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Bloom syndrome protein; RecQ protein-like 3; DNA helicase RecQ-like type 2; BLM; RECQ2; RECQL3

Composition

C86H144N32O31S1

Sequence

The synthetic peptide used to raise the antibody Cat. No. 200159 is selected from a sequence within the N-term region of human BLM. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Release Date

Monday, December 17, 2012

Subcategory