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Enzymes

CYLD Peptide

$50.00
SKU: 350498
CYLD is a negative regulator of TRAF2 and NF-kappa B signaling pathway. CYLD has a deubiquitinating activity that is directed towards non-Lys48-linked polyubiquitin chains. Defects in CYLD are the cause of familial cylindromatosis, a highly tumor type-specific disorder.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Pathway and Disease 
Cancers
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Probable ubiquitin carboxyl-terminal hydrolase CYLD; Ubiquitin thioesterase CYLD; Ubiquitin-specific-processing protease CYLD; Deubiquitinating enzyme CYLD; CYLD1
Composition 
C97H141N25O31S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200136 is selected from a sequence within the N-term region of human CYLD. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2185.4 g/mol
Unit 
0.1 mg

TYRO10 Peptide

$50.00
SKU: 350493
TYRO10 (DDR2) is a tyrosine kinase receptor for fibrillar collagen that mediates fibroblast migration and proliferation. TYRO10 contributes to cutaneous wound healing.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cell Motility
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Discoidin domain-containing receptor 2; Discoidin domain receptor 2; DDR2; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO 10; Neurotrophic tyrosine kinase, receptor-related 3; CD167b antigen; NTRKR3
Composition 
C92H126N22O29S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200131 is selected from a sequence within the center region of human TYRO10. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2036.2 g/mol
Unit 
0.1 mg

STK11 Peptide

$50.00
SKU: 350490
STK11, a CAMK Ser/Thr protein kinase, has an essential role in G1 cell cycle arrest. STK11 phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Defects in STK11 are a cause of predisposition to benign and maligant tumors including gastrointestinal and testicular cancers (Peutz-Jeghers syndrome).
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Pathway and Disease 
Cancers
Endocrine System
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Serine/threonine-protein kinase 11; Serine/threonine-protein kinase LKB1; Renal carcinoma antigen NY-REN-19; STK11; LKB1; PJS
Composition 
C95H167N31O24S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200128 is selected from a sequence within the N-term region of human STK11. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2159.6 g/mol
Unit 
0.1 mg

SPHK1 Peptide

$50.00
SKU: 350489
SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Pathway and Disease 
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Sphingosine kinase 1; SK 1; SPK 1; SPHK1; SPHK; SPK
Composition 
C64H107N21O18S2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200127 is selected from a sequence within the N-term region of human SPHK1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1522.8 g/mol
Unit 
0.1 mg

SMURF1 Peptide

$50.00
SKU: 350487
SMURF1 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and directly transfers the ubiquitin to targeted substrates. SMURF1 interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Pathway and Disease 
Folding
Sorting and Degradation
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Smad ubiquitination regulatory factor 1; E3 ubiquitin-protein ligase SMURF1; Smad-specific E3 ubiquitin ligase 1; hSMURF1
Composition 
C72H120N26O25S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200125 is selected from a sequence within the center region of human SMURF1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1781.9 g/mol
Unit 
0.1 mg

RYK Peptide

$50.00
SKU: 350485
RYK is a potential growth factor receptor protein tyrosine kinase.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cell Growth and Death
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Tyrosine-protein kinase RYK
Composition 
C88H146N24O29S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200123 is selected from a sequence within the N-term region of human RYK. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2036.3 g/mol
Unit 
0.1 mg

PKM2 Peptide

$50.00
SKU: 350484
PKM2 is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP for generating ATP. There are 4 isoenzymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is the major isozyme in liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Pathway and Disease 
Cancers
Carbohydrate Metabolism
Endocrine System
Energy Metabolism
Metabolic Disorders
Nucleotide Metabolism
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; Pyruvate kinase 2/3; Cytosolic thyroid hormone-binding protein; CTHBP; THBP1; PKM2; PK2; PK3; PKM
Composition 
C82H128N24O19S2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200122 is selected from a sequence within the C-term region of human PKM2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1818.1 g/mol
Unit 
0.1 mg

PIM2 Peptide

$50.00
SKU: 350483
PIM2 is a CAMK Ser/Thr protein kinase highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Pathway and Disease 
Cancers
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Serine/threonine-protein kinase Pim-2; Pim-2h; PIM2
Composition 
C70H119N19O23S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200121 is selected from a sequence within the C-term region of human PIM2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1626.8 g/mol
Unit 
0.1 mg

PIM1 Peptide

$50.00
SKU: 350482
PIM1, a CAMK Ser/Thr protein kinase, plays a role in signal transduction in blood cells. PIM1 contributes to both cell proliferation and survival, providing a selective advantage in tumerogenesis. PIM1 is strongly induced in leukocytes by the JAK/STAT pathway in response to cytokines.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cancers
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Proto-oncogene serine/threonine-protein kinase pim-1
Composition 
C89H144N24O29S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200120 is selected from a sequence within the C-term region of human PIM1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2046.3 g/mol
Unit 
0.1 mg

PI3KCA Peptide

$50.00
SKU: 350481
PIK3CA, a PI3/PI4 kinase, phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal, breast and epithelial ovarian cancers.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Pathway and Disease 
Carbohydrate Metabolism
Cell Communication
Cell Growth and Death
Cell Motility
Endocrine System
Immune System
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; PI3-kinase p110 subunit alpha; PtdIns-3-kinase p110; PI3K; PIK3CA
Composition 
C93H143N23O34S3
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200119 is selected from a sequence within the C-term region of human PI3KCA. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2223.4 g/mol
Unit 
0.1 mg

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