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Enzymes

Slicer Antibody

$220.00
SKU: 200187
Eukaryotic translation initiation factor 2C 2, also known as Slicer protein or Argonaute-2, provides endonuclease activity to RNA-induced silencing complexes (RISC). Slicer cleaves siRNA/mRNA heteroduplexes bound to RISC. Slicer is essential for embryonic development and RNA-mediated gene silencing (RNAi). Slicer is localised in processing bodies (P bodies) that contain decapping enzymes, a 5'-to-3' exoribonuclease, LSm proteins, and RNAi machinery components.
The Slicer Antibody is used in Western blot to detect Slicer in MDA-MB-435 cell lysate.
List price: $0.00
Price: $220.00

20S Proteasome Antibody

$220.00
SKU: 200179
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu and Glu adjacent to the cleavage site at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings resulting in a barrel-shaped structure.
The 20S Proteasome Antibody is used in Western blot to detect the 20S proteasome subunit in MDA-MB-435 cell lysate.
List price: $0.00
Price: $220.00

CYLD Antibody

$220.00
SKU: 200136
CYLD is a negative regulator of TRAF2 and NF-kappa B signaling pathway. CYLD has a deubiquitinating activity that is directed towards non-Lys48-linked polyubiquitin chains. Defects in CYLD are the cause of familial cylindromatosis, a highly tumor type-specific disorder.
The CYLD Antibody is used in Western blot to detect CYLD in HEK293 cell lysate.
List price: $0.00
Price: $220.00

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