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Transcription Factors

ASH-1 Antibody

$280.00
SKU: 252145
Achaete-scute homolog 1 (ASH-1) plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. ASH-1 is essential for the generation of olfactory and autonomic neurons. ASH-1 activates transcription by binding to the E box (5'-CANNTG-3').
List price: $0.00
Price: $280.00

KLF15 Antibody

$245.00
SKU: 252107
Krueppel-like factor 15 (KL15) is a transcriptional activator. KL15 binds to the GA element of the CLCNKA promoter. KL15 is highly expressed in liver, followed by heart, skeletal muscle, and kidney. KL15 is not expressed in bone marrow or lymphoid tissues.
List price: $0.00
Price: $245.00

KLF4 Antibody

$280.00
SKU: 252108
KLF4 (Krueppel-like factor 4) is a transcription factor, can act both as activator and as repressor. KLF4 binds the 5'-CACCC-3' core sequence of promoters, and also binds to its own promoter region of its own gene and can activate its own transcription. KLF4 regulates the expression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, in preventing their differentiation. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors.
List price: $0.00
Price: $280.00

RB (7E4B) Antibody

$220.00
SKU: 252623
Rb (Retinoblastoma-associated protein) is a key regulator of entry into cell division that acts as a tumor suppressor. Rb is directly involved in the heterochromatin formation by maintaining overall chromatin structure and constitutive heterochromatin by stabilizing histone methylation. Defects in Rb are a cause of retinoblastoma, bladder cancer and osteogenic sarcoma.
Rb staining in human esophagus and stomach. Paraffin-embedded human esophagus (left) and stomach (right) tissues are stained with RB (7E4B) Antibody (Cat. No. 252623) used at 1:200 dilution.
List price: $0.00
Price: $220.00

CREB-1 Antibody

$245.00
SKU: 252116
Cyclic AMP-responsive element-binding protein 1 (CREB-1) is a protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB-1 stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 is implicated in synchronization of circadian rhythmicity.
The CREB-1 Antibody is used in Western blot to detect the CREB-1 in human human prostatic cancer.
List price: $0.00
Price: $245.00

AEBP1 Peptide

$50.00
SKU: 350560
Adipocyte enhancer-binding protein 1 (AEBP1) up-regulates MAP-kinase activity leading to enhanced proliferation and reduced differentiation of the adipocyte. AEBP1 also up-regulates NF-kappa-B activity in macrophages via phosphorylation and subsequent degradation of I-kappa-B-alpha. This leads to enhanced macrophage inflammatory responsiveness. It can also act as a transcriptional repressor.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Translation Factors
Transcription Factors
Protein Kinases
Enzymes
Pathway and Disease 
Immune System
Signaling Molecules and Interaction
Transcription
and Translation.
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
AEBP1; ACLP; AE-binding protein 1; Aortic carboxypeptidase-like protein; Adipocyte enhancer-binding protein 1
Composition 
C93H136N18O36S1C93H136N18O36S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200198 is selected from a sequence within the N-term region of AEBP1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2114.2 g/mol
Unit 
0.1 mg
Accession No.  
Q14113

ELF3 Peptide

$50.00
SKU: 350550
ELF-3 is a transcriptional activator which binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate SPRR2A promoter.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Transcription Factors
Pathway and Disease 
Transcription
Translation
Signal transduction
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
ETS-related transcription fator Elf-3; E74-like factor 3; Epithelium-specific Ets transcription factor 1; ESE-1 Epithelium-restricted Ets protein ESX; Epithelial-restricted with serine box; ELF3; ERT; ESX; JEN
Composition 
C84H135N27O31S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200188 is selected from a sequence within the C-term region of ELF-3. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2051.2 g/mol
Unit 
0.1 mg
Accession No.  
P78545

Bmi1 Peptide

$50.00
SKU: 350547
Polycomb complex protein BMI-1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex that maintains the transcriptionally repressive state of many genes, including Hox genes throughout development. PcG PRC1 complex forms Polycomb bodies that act via chromatin remodeling and histone modification. BMI-1 cooperates with Myc oncogene to produce B-lymphomas.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Transcription Factors
Ubiquitins
Pathway and Disease 
Cancers
Folding
Sorting and Degradation
Transcription
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; PCGF4; RNF51
Composition 
C79H128N30O27S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200185 is selected from a sequence within the C-term region of human Bmi1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1962.1 g/mol
Unit 
0.1 mg
Accession No.  
P35226

PML Peptide

$50.00
SKU: 350546
Promyelocytic leukemia protein (PML) is a transcription factor involved in transcriptional regulation and nuclear protein sequestration, such as recruiting ELF4 into PML nuclear bodies. A chromosomal aberration involving PML is a cause of acute promyelocytic leukemia.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Transcription Factors
Ubiquitins
Pathway and Disease 
Cancers
Folding
Sorting and Degradation
Transcription
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Probable transcription factor PML; Tripartite motif-containing protein 19; RING finger protein 71; PML; MYL; RNF71; TRIM19; Promyelocytic leukemia protein
Composition 
C80H131N29O27S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200184 is selected from a sequence within the N-term region of human PML. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1963.1 g/mol
Unit 
0.1 mg
Accession No.  
P29590

NonO Peptide

$50.00
SKU: 350545
Non-POU domain-containing octamer-binding protein (NonO protein/p54nrb) is a DNA- and RNA-binding protein involved in several nuclear processes such as binding octamer sequence in dsDNA, pre-mRNA splicing, and interacting with U5 snRNA. NonO is found in paraspeckle bodies, which contain several RNA-binding proteins and nuclear-retained CTN-RNA. A chromosomal abberation involving NonO protein is a cause of colon carcinoma.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Transcription Factors
Pathway and Disease 
Cancers
Replication and Repair
Transcription
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Non-POU domain-containing octamer-binding protein; NonO protein; 54 kDa nuclear RNA- and DNA-binding protein; p54(nrb); p54nrb; 55 kDa nuclear protein; NMT55; DNA-binding p52/p100 complex, 52 kDa subunit; NONO; NRB54
Composition 
C84H129N27O23S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200183 is selected from a sequence within the C-term region of human NonO. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1917.1 g/mol
Unit 
0.1 mg
Accession No.  
Q15233

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