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Transporters

GLUT2 Peptide

$80.00
SKU: 300121

Glucose transporter type 2 (GLUT2 or SLC2A2) is a facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells. GLUT2 is also part of the glucose-sensing mechanism of the beta cell and participate with the Na+/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Defects in GLUT2 are the cause of Fanconi-Bickel syndrome, characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose.

List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Protein Family 
Transporters
Pathway and Disease 
Carbohydrate Metabolism
Membrane Transport
Metabolic Disorders
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Solute carrier family 2 facilitated glucose transporter member 2; Glucose transporter type 2 liver; GLUT-2; SLC2A2; GLUT2
Composition 
CHNO
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 250672 is selected from a sequence within the N-term region of human GLUT2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Tuesday, May 21, 2013
Subcategory 
Blocking Peptide
Synthetic Peptide
Unit 
0.1 mg
Accession No.  
P11168

MDM2 Antibody

$265.00
SKU: 254518

MDM2 mediates ubiquitination of p53/TP53, leading to its degration by the proteasome. MDM2 inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding to their respective transcriptional activation domains. MDM2 also acts as an ubiquitin ligase towards itself and ARRB1, permits the nuclear export of TP53/p53, and promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein.

The MDM2 Antibody (Cat. No. 254518) is used in Western blot to detect MDM2 in mouse liver tissue.
List price: $0.00
Price: $265.00

TRAK2 Antibody

$280.00
SKU: 252041
Trafficking kinesin-binding protein 2 (TRAK2) regulates endosome-to-lysosome trafficking of membrane cargo, including EGFR. TRAK2 interacts with GABA-A receptor and O-GlcNAc transferase, HGS, RHOT1/Miro-1, and RHOT2/Miro-2.
List price: $0.00
Price: $280.00

CFTR Peptide

$50.00
SKU: 350548
Cystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Receptors and Channels
Transporters
Pathway and Disease 
Membrane Transport
Metabolic Disorders
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Cystic fibrosis transmembrane conductance regulator; CFTR; cAMP-dependent chloride channel; ATP-binding cassette transporter sub-family C member 7; ABCC7
Composition 
C98H160N30O28S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200186 is selected from a sequence within the N-term region of human CFTR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2238.5 g/mol
Unit 
0.1 mg
Accession No.  
P13569

SUFU Peptide

$50.00
SKU: 350501
SUFU is a negative regulator in the hedgehog signaling pathway that down-regulates GLI1-mediated transactivation of target genes. Defects in SUFU are a cause of medulloblastoma, a malignant and invasive embryonal tumor of the cerebellum.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Transporters
Pathway and Disease 
Cancers
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Suppressor of fused homolog; SUFUH; SUFU
Composition 
C101H148N22O31S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200139 is selected from a sequence within the C-term region of human SUFU. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2198.4 g/mol
Unit 
0.1 mg
Accession No.  
Q9UMX1

Beta-arrestin 1/2 Peptide

$80.00
SKU: 300120
Beta-arrestins function in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein. Beta-arrestin binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and recruiting the GPRCs to the adaptor protein 2 complex 2 (AP-2) in clathrin-coated pits (CCPs). This antibody recognizes beta-arrestin-1 and beta-arrestin-2. The extent of beta-arrestin involvement appears to vary significantly depending on the receptor, agonist and cell type.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Protein Family 
Receptors and Channels
Transporters
Pathway and Disease 
Signal Transduction
Immune System
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
beta-arrestin 1; beta-arrestin 2; beta-arrestin 1/2; Beta-arrestin-1/2; Beta-arrestin-1; Arrestin beta-1; ARRB1; Beta-arrestin-2; Arrestin beta-2; ARRB2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 251344 is selected from a sequence within the N-term region of human beta-arrestin 1/2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
Unit 
0.1 mg
Accession No.  
P49407
P32121

ABCB6 Peptide

$80.00
SKU: 300116
ATP-binding cassette sub-family B member 6, mitochondrial (ABCB6) binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. ABCB6 plays a crucial role in heme synthesis. Depletion of ABCB6 by RNAi abrogates heme biosynthesis. Overexpression enhances porphyrin biosynthesis.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Protein Family 
Transporters
Pathway and Disease 
Membrane Transport
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
ABCB6; ATP-binding cassette sub-family B member 6, mitochondrial; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; Ubiquitously-expressed mammalian ABC half transporter; P-glycoprotein-related protein; MTABC3; PRP; UMAT
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 250549 is selected from a sequence within the N-term region of human ABCB6. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
Unit 
0.1 mg
Accession No.  
Q9NP58

OAT-1 Peptide

$80.00
SKU: 300115
The organic anion transporter 1 (OAT-1 or SLC22A6) is localized to the basolateral membrane of renal tubular epithelial cells and plays a critical role in the excretion and detoxification of anionic compounds. OAT-1 functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). OAT-1 mediates the sodium-independant uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV) and many other organic compounds.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Protein Family 
Transporters
Pathway and Disease 
Folding
Sorting and Degradation
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Solute carrier family 22 member 6; Organic anion transporter 1; OAT1; Renal organic anion transporter 1; ROAT1; PAH transporter; PAHT; SLC22A6
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 250797 is selected from a sequence within the center region of human OAT-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
Unit 
0.1 mg
Accession No.  
Q4U2R8

Katacalcin Peptide

$146.00
SKU: 350231

Katacalcin is a potent plasma calcium lowering peptide. Katacalcin belongs to the calcitonin family, that causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of these ions in the bones. Calcitonin is cleaved into 2 chains, calcitonin and katacalcin.

List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $146.00
Protein Family 
Transporters
Pathway and Disease 
Endocrine System
Signaling Molecules and Interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Katacalcin; Calcitonin carboxyl-terminal peptide; CCP; PDN1; Calcitonin; CALCA; CALC1
Composition 
C97H154N34O36S2
Sequence 
Human: H-Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn-OH or H-DMSSDLERDHRPHVSMPQNAN-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
2436.64 g/mol
Unit 
1 mg
Accession No.  
P01258

Pep-1 Peptide

$134.00
SKU: 350333
Transports fullength proteins to the nucleus of the cell.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $134.00
Protein Family 
Transporters
Pathway and Disease 
Membrane Transport
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
NONE
Composition 
C136H195N35O33
Sequence 
H-Lys-Glu-Thr-Trp-Trp-Glu-Thr-Trp-Trp-Thr-Glu-Trp-Ser-Gln-Pro-Lys-Lys-Lys-Arg-Lys-Val-OH or H-KETWWETWWTEWSQPKKKRKV-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
2848.29 g/mol
Unit 
1 mg
Accession No.  

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