Human PDGF-BB

Recombinant Active Protein

Cat. No.

600165

Unit

0.01 mg

Price $235.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

PDGF (Platelet-derived growth factor) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by Interleukin-1, Interleukin-6, TNF-alpha, TGF-beta and EGF. PDGF-BB Human Recombinant is a homodimeric non-glycosylated polypeptide chain containing 109 amino acids with a MW of 24.3 kDa.

Spec Container

Datasheet

Format

Each vial contains 10 ug protein lyophilized in 10 mM acetic acid. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Alternate Names

Platelet-derived growth factor subunit B; PDGF subunit B; Platelet-derived growth factor B chain; Platelet-derived growth beta polypeptide; PDGF-2; c-sis; Becaplermin; PDGFB; PDGF2; SIS

Accession No.

P01127

24300 Da

Sequence

SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIGIVRK KPIFKKATVT LGDHLACKCE TVAAARPVT

Source

E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.

Purity

Purity > 95% as determined by reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and quantitation on SDS-PAGE against a known standard.

Application Notes

PDGF-BB is fully biologically active when compared to standard. The ED50, calculated by the dose-dependent proliferation of BALB/c 3T3 indicator cells is < 1.86 ng/ml.

Storage

Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

Images

Citations

Product Citations

Lim S et al. Cardiovascular Research. 2011. 90: 383-393. PMID# 21245056.

Related Products

Lysate Products
Product Name	Applications	SKU	Price
A549 Lysate	WB	450278	$90.00
ANP32A 293 Cell Lysate	ELISA, WB, IP	407823	$392.00

Antibody Products
Product Name	Applications	SKU	Price
Anti-human IgA Antibody	E	250114	$165.00
Anti-human IgE (1A2) Antibody	E, WB	252516	$220.00
Anti-human IgE (1A2) Antibody	E, WB	252517	$275.00
Anti-human IgE Antibody	E, WB	250140	$165.00
Anti-human IgG (4D2D) Antibody	E, WB	252595	$165.00
Anti-human IgG Antibody	E	250116	$165.00
Anti-human IgG-Fc (2E4) Antibody	WB	252877	$308.00
Anti-human IgG-Fc (4A10) Antibody	WB, IF	252867	$308.00
Anti-human IgM Antibody	E, FC	250113	$165.00
Anti-human IgM Antibody	E, FC, IHC	250928	$220.00
Anti-human IgM Antibody	FC	250929	$275.00
Anti-human IgM Antibody	FC	250930	$275.00
Anti-human IgM Antibody	E	254517	$195.00
Anti-human kappa Ig Antibody	FC, IF	251099	$275.00
Anti-human kappa Ig Antibody	E, FC	250987	$220.00
Anti-human kappa Ig Antibody	FC, IF	251043	$275.00
Anti-human lambda Ig Antibody	E, FC, IHC	250186	$275.00
Anti-human lambda Ig Antibody	E, FC, IHC	250185	$245.00

For research use only, not for diagnostic or therapeutic procedures.

You are here

Human PDGF-BB

Order

Order directly from

Spec Container

Related Products