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ADAM-TS4 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
251975
Unit 
0.1 mg
Price $323.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS4) cleaves aggrecan, a cartilage proteoglycan, and is involved in its turnover. ADAM-TS4 plays an important role in the destruction of aggrecan in arthritic diseases. ADAM-TS4 is a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. ADAM-TS4 cleaves aggrecan at the '392-Glu-|-Ala-393' site.