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AMIGO-2 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
252046
Unit 
0.1 mg
Price $323.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

Amphoterin-induced protein 2 (AMIGO-2) is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO-2 mediates homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO-2 contributes to signal transduction through its intracellular domain, and is be required for tumorigenesis of a subset of gastric adenocarcinomas. AMIGO-2 is differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.